James Holmes, 24, faces 12 charges of first-degree murder, 12 charges of murder with extreme indifference and 116 counts of attempted murder.
A dozen people died and 58 were injured after a gunman opened fire at random the crowded movie theatre on 20 July.
As of Sunday, 10 victims of the 20 July shooting remained in hospital, four of them in a critical condition.
Ashley Moser, the critically injured mother of a six-year-old girl killed in the rampage in Aurora, near Denver, has suffered a miscarriage, her family said on Saturday.
Mr Holmes is also accused of wiring his apartment with enough explosives to have destroyed the entire building had they been detonated. It took authorities several days to dismantle the booby traps.
Court documents filed on Friday by defence lawyers said the suspect had been under the care of a psychiatrist at the University of Colorado Denver, where he had been in the process of dropping out as a neuroscience PhD student.
Monday's hearing was also expected to address a package - discovered in a campus mailroom three days after the shootings - which the suspect addressed to that psychiatrist, Dr Lynne Fenton.
The package reportedly contained descriptions of an attack, including drawings of a stick-figure gunman shooting people.
The defence team is seeking a court order requiring prosecutors to immediately turn over all evidence relating to the seizure of a package, citing doctor-patient privilege.
They have also lodged a motion to find out who leaked the existence of the package to the media, which they say could jeopardise the suspect's right to a fair trial.
Prosecutors have said it will be several weeks before a decision is made on whether or not to seek the death penalty in the case.
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