Activists in the city say supplies of food and cooking gas are running low.
Fresh clashes and attacks by helicopter gunships have been reported, but rebels say they have held on to the key district of Salah al-Din.
The UN says 200,000 people have fled the fighting in the city.
But Melissa Fleming, a spokeswoman for the UNHCR refugee agency, said many more had been unable to leave because they did not have the means to make the journey, or felt it would be too dangerous.
An estimated 15,000-16,600 frightened residents have sought refuge in schools, mosques and public buildings in the city, she said.
"There are 32 schools in Aleppo that we've identified and in each of those schools, we have heard, or we have witnessed, that 250-300 people were packed inside, many of these families, kids.
"And then in university dormitories, there are a total of some 7,000 people hoping to seek safety from the continuing shelling."
Mohammed Saeed, an activist living in the city, told the Associated Press that the situation for residents was "very bad".
"There is not enough food and people are trying to leave. We really need support from the outside. There is random shelling against civilians," he said.
"The city has pretty much run out of cooking gas, so people are cooking on open flames or with electricity, which cuts out a lot."
There are also reports that citizens remaining in the city face long queues for bread.
On Tuesday, there were fresh reports of clashes and attacks by helicopter gunships in Aleppo as the Syrian army offensive entered its fourth day.
State TV said Syrian forces were inflicting heavy losses on "terrorist groups" in Aleppo and also claimed government successes in Homs.
On Monday, it reported that the army had won complete control over Salah al-Din, one of the areas of Aleppo where rebel fighters from the Free Syrian Army had become entrenched.
However, one rebel commander in the area, Col Abdel-Jabbar al-Oqaidi, told the Reuters news agency on Tuesday that the government efforts to gain control of Salah al-Din had failed for three days running.
"It has suffered heavy losses in human life, weapons and tanks, and it has been forced to withdraw," said Col Oqaidi of the Joint Military Council, one of several rebel groups in Aleppo. He estimated that there were at least 3,000 rebel fighters in the entire city.
Analysts say Salah al-Din provides an important route for Syrian troop reinforcements coming from the south.
Activists also report heavy shelling and helicopter gunship attacks around the Sakhour quarter on the north-east side of Aleppo, as well as near the headquarters of the feared Air Force Intelligence agency, to the west of the city.
Turkey: 44,188 Anxious Turks wait for endgame
Jordan: 36,824 Jordan's desert refugee camp
Lebanon: 32,796 Defiance at Lebanon frontier
Iraq: 8,445 Iraq pressurised by tribal ties
Estimated internally displaced: 1,000,000
Source: UNHCR, 31 July 2012
The BBC's Ian Pannell, who has just left Aleppo, says knowing who is firing where is impossible, as gunfire echoes around the city.
State television completely ignored events in Aleppo in its early morning news programmes on Tuesday, the BBC's Jim Muir in Beirut says, but later bulletins carried reports of Syrian forces inflicting heavy losses on ''terrorist groups'' in Aleppo districts.
Correspondents say neither side can afford to lose Aleppo, Syria's largest city and its industrial and financial centre.
Until this month it had been spared the bloodshed seen in other cities since the uprising began in March 2011.
Meanwhile the US and Turkey have agreed to step up efforts to achieve "political transition" in Syria that would include the departure of President Bashar al-Assad, the White House said.
In a phone call on Monday, US President Barack Obama and Turkish Prime Minister Recep Tayyip Erdogan agreed to help the growing numbers of refugees - both inside Syria and in neighbouring countries.
Turkey has been a staunch critic of President Assad and has given refuge to large numbers of army defectors.
Thousands of Syrian refugees are also living in refugee camps on the Turkish side of the countries' long border.
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